Completely overlooked is the point that Jon Matonis clearly pointed out.
The dynamic duo of pseudonymus digital currency + provably fair gaming = a dramatically lowered barrier to opening and operating an online gaming service.
Before, only the well funded ventures could survive long enough to get through setting up in a proper jurisdiction where that type of service is allowed, working with payment processors, working with online gaming regulatory organizations, possibly going through an audit, etc.
Once the Farmville and html5 game developers realize that there's not much stopping them from offering online wagering, the next online gaming success story could come from the unlikeliest of sources.