No one is too big to fail, and of all the globally positioned CEX, the one you mention is certainly the one that is most talked about in a negative context. Some would say that it is only because the competition is trying to steal a part of their users, and some others would say that you cannot hide in the gray zone forever and that sooner or later you will become a target.
They have been a target for quite some time now, and it will always be a target. Still best to have that safety precaution in place and not put everything in one basket.Generally speaking, such companies have turned into a ticking bomb and threatens to cause enormous damage if (and when) it explodes. The advice that is constantly repeated is even more relevant today, which is to not use any CEX as a wallet for storage, but only for trading.
It is going to cause damage when it explodes. This is where DEX would come in and make trading safe. Because you have to admit that you would want to put more on your portfolio if you want to profit more, and sometimes that's a lot, and you cannot do anything about it if the one who crumbles the CEX you are trying to use. 
