I was also wondering recently if there could be some sort of an exploit/inside job against Gox's stash which manifested itself as a lot of double-spends. ...
I ponder no longer.
I had imagined that Gox was taking their own database as a source of truth for accounting purposes and that was probably at the root of the problem. This seems to be true.
Looks like it probably was not an inside job as I had hypothesized although the potential exists for insiders to have been re-issue payments even after understanding that it would cause a loss. That's not necessary to explain the observations though.
It would be fun to know how much Mt. Gox (and probably others) lost to this simplistic form of attack.
One way or another, it is pretty sleazy for Karpeles to try to blame the issue on the Bitcoin protocol when they tried to write a processor client without even troubling themselves to ponder the information described on the wiki page.