Accept and make hundreds of payouts every hour automatically?
What exactly are you trying to build that is going send out hundreds of payouts every hour? You should think about grouping the payments into batches and use blockchain.info's send multiple feature if that's a possibility for you. If not, I have been a fan of block.io lately, not sure of their API requests off the top of my head, but they have been better than bc.info. Ultimately for creating something with this much volume, you should really consider running your own node with digitalocean and then handle all the requests with bitcoind RPC.
