You are most likely to have side effects from dietary supplements if you take them at high doses or instead of prescribed medicines, or if you take many different supplements. Some supplements can increase the risk of bleeding or, if taken before surgery, can change your response to anesthesia.
7 Popular Supplements With Hidden Dangers
1. Vitamin D: Too Much Can Harm Your Kidneys
Vitamin D promotes calcium absorption in the body, and getting enough is central to health and well-being, offering the promise of protecting bones and preventing bone diseases like osteoporosis. Supplemental vitamin D is popular because it’s difficult (if not impossible) to get enough from food. Also, as the Centers for Disease Control and Prevention (CDC) notes, our bodies make vitamin D when bare skin is exposed to sunlight, but increased time spent indoors and widespread use of sunblock has minimized the amount of vitamin D many of us get from sun exposure.But enthusiasm for vitamin D supplements is outpacing the evidence. As it turns out, when healthy women take low doses of vitamin D (up to 400 international units, or IU) it does not necessarily prevent them from breaking bones, according to a U.S. Preventive Services Task Force report published in May 2013 in the journal Annals of Internal Medicine.
And taking high doses is not a good option. In healthy people, vitamin D blood levels higher than 100 nanograms per milliliter (ng/mL) can trigger extra calcium absorption — and lead to muscle pain, mood disorders, abdominal pain, and kidney stones, notes the Cleveland Clinic. It may also raise the risk of heart attack and stroke.
“More is not necessarily better when it comes to micronutrient supplements,” says Manson.
The outlook is different for women who are over age 71, deficient in vitamin D, live in institutions, or have dark skin pigmentation. For them, the National Academy of Medicine reports, vitamin D supplements prescribed by a doctor are beneficial. To achieve vitamin D recommendations — 600 IU per day for people 1 to 70 years old and 800 IU per day for individuals 71 or older — include whole foods, such as salmon, tuna, milk, mushrooms, and fortified cereals in your daily diet. You can also spend a brief time in the sun without sunblock — about 10 to 15 minutes a day, according to the NIH.
2. St. John’s Wort: Avoid Drug Interactions
St. John’s wort is a plant used as a tea or in capsules to treat mild depression, anxiety, and sleep disorders. Small studies have shown St. John’s wort to be effective at treating mild depression. For example, a review published March 2017 in the Journal of Affective Disorders looked at of 27 clinical trials with a total of 3,808 patients and concluded that the herbal remedy worked as well as certain antidepressants at decreasing symptoms of mild to moderate depression.But, says Denise Millstine, MD, an internist in the department of integrative medicine at Mayo Clinic in Phoenix, Arizona, “The biggest issue with St. John’s wort is its medication interactions.”
A study published in July 2014 in the Journal of Alternative and Complementary Medicine found that 28 percent of the time St. John’s wort was prescribed between 1993 and 2010, it was administered in dangerous combinations with antidepressant or anti-anxiety medication, statins, the blood-thinning drug warfarin, or oral contraceptives. For example, combining St. John’s wort with an antidepressant can cause serious complications, including a life-threatening increase in the brain chemical serotonin, according to the National Center for Complementary and Integrative Health.
3. Calcium: The Excess Settles in Your Arteries
Calcium is essential for strong bones and a healthy heart, but too much is not a good thing. In fact, an excess of calcium, which is described by the NIH as more than 2,500 mg per day for adults ages 19 to 50, and more than 2,000 mg per day for individuals 51 and over, can lead to problems.
According to the Cleveland Clinic, “Researchers believe that without adequate vitamin D to help absorb it, the extra calcium settles in the arteries instead of the bones.”In addition, an analysis of 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, published October 10, 2016, in the Journal of the American Heart Association, suggested that taking calcium supplements may increase plaque buildup in the aorta and other arteries. In contrast, a diet high in calcium-rich foods, such as dairy products and leafy greens, appeared to be protective.
“Get calcium from your diet if you can,” advises Dr. Millstine, noting that research shows that calcium is better absorbed through food than through supplements.
The National Institutes of Health (NIH) recommends 1,000 mg of calcium a day for women ages 19 to 50, and 1,200 mg a day for women 51 and older. The recommendation for men ages 19 to 70 is 1,000 mg a day, and 1,200 mg a day for men 71 and older. According to the U.S. Department of Agriculture (USDA), 6 ounces of plain low-fat yogurt contains about 311 mg of calcium, a little less than one-third of the daily recommendations. Other good calcium sources include tofu, nonfat milk, cheese, fortified cereal, and juices.Calcium deficiency, or hypocalcemia, may be detected by routine blood tests. If you have low calcium blood levels, your doctor may prescribe a calcium supplement.
4. Multivitamins and Multiminerals: No Substitute for a Healthy Diet
Think that a healthy lifestyle requires not just eating good-for-you foods, exercising, and getting enough sleep, but also taking a daily multivitamin-multimineral supplement? You may be surprised to learn that the jury’s still out on whether those supplements are truly helpful.
One surprising study published in the journal JAMA Internal Medicine, which examined data from nearly 40,000 women over 19 years, found that, on average, women who took supplements had an increased risk of dying compared with women who didn’t take supplements. Multivitamins also did little or nothing to protect against common cancers, cardiovascular disease, or death.
However, more recent research has found benefits to taking multivitamins. For example, a study published August 9, 2017, in the journal Nutrients concluded that frequent use of multivitamin and mineral supplements helped prevent micronutrient shortfalls that might otherwise cause health problems.
For women of childbearing age, taking prenatal vitamins with folic acid is recommended by the American College of Obstetricians and Gynecologists to help prevent birth defects. Multivitamins might also be prescribed by your doctor if you have malabsorption syndrome, a condition in which the body does not properly absorb vitamins and minerals.
But for healthy people, Manson says, “a supplement can never be a substitute for a healthy diet."
5. Fish Oil Supplements: Choose Fish or Flaxseed Instead
Rich in omega-3 fatty acids, fish oil has been touted as a means to reduce heart disease. However, more and more evidence shows that fish oil supplements have questionable heart benefits. A study published January 3, 2019, in The New England Journal of Medicine (NEJM) found that omega-3 fatty acid supplements did nothing to reduce heart attacks, strokes, or deaths from heart disease in middle-aged and older men and women without any known risk factors for cardiovascular disease. An earlier study, published in May 2013 in NEJM, looked at people at high risk for cardiovascular disease and also reported no benefit.
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According to the NIH, omega-3 deficiency is “very rare in the United States.” Still, many people fail to consume enough omega-3s daily for optimal health. The best way to get adequate amounts is by eating a variety of foods that are rich in them, including:
Fish and other seafood, especially cold-water fatty fish, such as salmon, mackerel, tuna, herring, and sardines
Nuts and seeds, such as flaxseed, chia seeds, and walnuts
Plant oils, such as flaxseed oil, soybean oil, and canola oil
Fortified foods, such as certain brands of eggs, yogurt, juices, milk, and soy beverages.
6. Kava: Overuse Can Harm Your Liver
Kava is an herb that in concentrated forms has been used to treat general anxiety disorder with some success. An Australian study published online in 2015 in the journal Trials found that the South Pacific plant can be an effective alternative treatment to prescription medication for people diagnosed with generalized anxiety disorder (GAD). An earlier, smaller study, published in October 2013 in the Journal of Clinical Psychopharmacology, also showed that taking kava significantly reduced anxiety compared with a placebo in people with GAD.However, taking too much kava, or taking it for too long, has been linked to serious liver damage, including hepatitis, cirrhosis, and liver failure. As a result, according to the NIH, the FDA has warned that people, especially those with liver disease or liver problems, or those who are taking drugs that can affect the liver, should talk to their healthcare practitioner before using kava. In addition, the National Center for Complementary and Integrative Health reports that heavy consumption of kava has been associated with heart problems and eye irritation.
7. Soy Isolate: Careful With the Estrogen
Tofu, tempeh, and soy milk are all good sources of protein, fiber, and a number of minerals. Some women also take soy in supplement form because the plant contains estrogen-like compounds called isoflavones that may help relieve symptoms of menopause. However, concerns have been raised that the isoflavones in soy supplements may contribute to an increased risk of breast cancer.
The good news is that large-scale studies have not shown any increased breast cancer risk from eating whole soy foods, such as tofu and edamame, according to the Dana Farber Cancer Institute in Boston.
In fact, at least one study, published March 6, 2017, in the journal Cancer, which looked at 6,235 breast cancer survivors, linked eating the equivalent of one serving of soybeans a week to a 21 percent lower risk of death from all causes during the nearly 10-year follow-up period.
But not enough research has been done on soy protein isolate (SPI) — the powder formed by removing the protein from the rest of the plant — to know its effect on breast cancer risk, Millstine says. (In addition to supplements, SPI is often found in power bars, veggie burgers, and some soups, sauces, smoothies, and breakfast cereals.)
The bottom line: “If you’re concerned about breast cancer, stay away from soy supplements and soy-based protein,” Millstine advises. “Soy intake from foods has not been shown to be of concern though.”
https://www.everydayhealth.com/news/supplements-risks-every-women-should-know/