How do I run them off different chains?
So you have a couple cables off the power supply providing a few molexes each. You shouldn't hook up every powered extender to the same cable coming out of the power supply. If I recall correctly, the max that you'd safely want to pull from a molex is 75W - exactly what the slot can provide by spec. So to be absolutely safe, try to use a different molex cable coming out of the PSU for each powered extender. However, if you must, I personally would feel safe with two on the same cable if it's a high quality PSU (but don't do it if you don't have to).