I can see many ASIC buyers cashing out immediately as they mine in order to recoup hardware cost and to also try to buy more ASICs to get a larger market share of hash power.
Selling pressure will mount.
Initially I can see some miners doing that. Assuming the current GPU miners all quit (much like the CPU miners) the net effect of ASICs will be to add a couple 0's to the difficulty, and increase the initial investment of those that wanted to stay in the game and purchased new equipment. Those that remain will still be fighting over the same (halved) pie, and I think we would have a spread of hoarders to sellers similar to what we have now. It would be interesting to see a chart based on the projected efficiency of ASICs, taking into consideration network adoption. I've seen charts saying "zomg I can make 2500% a year if I buy ASIC", but I saw those same charts when we switched to GPUs.
Mining for me has always been one question: Will the price of bitcoins increase enough to mitigate the effects of rising difficulty? This is a very bullish stance obviously, and I could have made significantly more money by simply buying coins outright, but I prefer to contribute to making the community stronger. As it stands now, I "may" break even next year, depending on how long it takes the ASIC trolls to get product to market.