I have always wanted to get into mining, but know I missed the prime time. If I were to invest in an ASIC/ASICs, is there a chance I could make profit off of it?(or at least pay it off). When they first come out, will that be the best time to buy them?
Well it's all speculation. I don't want to try and estimate if/when you'd make money by investing in ASIC hardware. The only thing that seems certain is that if ASIC turns out to produce anywhere near it's estimated hashes/second with as many people as have preordered the gear already that trying to mine on non-ASIC gear will be near useless.
If I were forced to guess, I would say that there would be a spike in profit for those that were the first to preorder and thus had the hardware in the network first. Then as the hardware becomes more available all the miners will be using the gear and the investment to return will be about the same.
Also of note, is the number of bitcoins to enter the economy per day is going to half probably around the end of this year (December?). How that plays out with the bitcoin value might affect your calculations as well.