First I want to see Bitcoin make it big in one market alone. The only one it has had any real effect so far is Silk Road, probably because with SR it's the easiest fit. I see a lot of potential for many other markets though, from virtual commodity markets to online gambling and then basically to anything that involves small transactions.
Also I don't think it's always necessary to think of it from the perspective of the user. A lot of enterpreneurs and companies that receive a lot of small transactions just love Bitcoin because it's so much cheaper, they need to give less away to middle men. There are also no chargebacks. As long as using Bitcoin is made easy for their customers (think bitpay and bitcoinspinner for starters), I could see companies pushing for Bitcoin usage.
The biggest problem right now are the uncertainties concerning the legal status of Bitcoin, how it's regulated and then of course the volatility of the exchange rate is another problem. Even with these concerns I feel that unless something fatal happens, Bitcoin will do fine. It's just a matter of time.