Indeed, accounts that have high followers and reach certainly are a luring attempt for hackers to attempt to exploit the target. That is why Youtube live cryptocurrency scams are populous, and in some degree scammers try to deceive their target by interacting with user who have a high user base. So in that sense, those who have influences have a high and diverse security risk.
What is essential is to apply basic digital security recommendations, for each people no matter whether they got a high likelihood of being targeted or not. That is because SMS 2FA is truly ineffective.