If you want to put on 10 GPU's on one board, get ready for a challenge! If I were you, I would spend a few months mastering 2 cards on one board. Once you have that under control, you can add more if you want. I used to run 6 on a board at once, but I went back to: 2 cards, 1 CPU, 1 Power supply. For me this was a decision about "manageability" more than it was about efficiency. The only real cost advantage of 10 GPU / 1 MOBO is the cost of the board, which you will consume quickly with the pci extentions ribbons and daisy chaining the all of the power supplies together. Then you have a MASSIVE amount of heat with which to contend.