Funding account w/ 2K @ 10:1 = 20K Tradable, use 2K/BTC-ask=risk amount. You can handle much more than a 6% drop this way.
The leverage setting only determines your maximum allowed leverage.
Correct me if I understood something horribly wrong.
I didn't suggest leveraging the funds 10:1. I suggested using 10:1 leverage for a $2K account, and starting with a position valued at $2K. (this is a 1:1 bet, with 10:1 leverage to protect from downside) as the position value grows, continue to add to it in the same ratio (1:1, add your profits to the position) In this scenario, you'd buy put options to protect from significant downside, and set a stoploss way down to prevent liquidation (but also preventing your position from getting stopped out on a short term dip)
Since you're looking for a very high long term reward from the position, the acceptable downside on the position is increased, as it's likely viewed as temporary (i.e. I'm not worried at the moment if BTC hits $4, I have confidence in the future, so I accept a great deal of downside risk, and try to keep the ratio at 1:2 risk:reward, so I'm looking for significant upside.
Having 10:1 leverage, and using 100% of your available leverage seem to me to be different. I use the margin in my account as cushion against the downside (and drawdown from it). I would never recommend that someone enter a position valued at $20K on a 10:1 $2K account. It is probably a faster way to lose money than matches and gasoline.
If I wanted to enter a position that leveraged my funds 10:1 I'd want a 100:1 margin account.
Hopefully this is more clear. A more risk tolerant person might take a larger position, but I would recommend against it for all but the most aggressive and experienced traders.