One of the possibilities is that hacker actually came into possession of seed, the question is only in what way. Looks like nobody has read my post which tried to explain mysterious disappearance of funds from blockchain accounts, and this can be one such case.
I have evidence that some bitcoin address generation code in the wild is using private keys that can easily be discovered on a regular basis. This is either intentional or by mistake. Some wallets have been compromised by what is probably an innocent looking piece of code. Furthermore, someone has been siphoning bitcoin on a regular basis since 2014 from them. Whether they discovered this by accident (like I did) or are the ones who installed the code themselves, I don't know. It looks like either a clever exploit or a coding error. It could also be yet another piece of malware, however as I explain below, I feel this is less likely the case. In order to fully understand how this works and how I discovered it, please read on.
No matter what really happened in this case, the damage was made and very likely irreversible. It is an indisputable fact that online wallets are not safe place to keep crypto, but in case of Electrum as desktop wallet it was shown that human naivety and ignorance can also cause big losses. But sometimes bad things happen even though we have taken all possible measures, maybe this is such case.
https://bitcointalksearch.org/topic/thoughts-on-this-private-key-stealing-mystery-2488493