If you want to get 'back to normal' i assume you mean that every transaction should be confirmed?
If this is the case you can do a child-pays-for-parent as others already mentioned.
You have to use the change-output of your unconfirmed transaction as a new input for a new transaction (to yourself).
The fee of this transaction has to be high enough to cover the fee for both of your transactions.
Unfortunately you can't explicitely do this in ledgers chrome app. But you can use electrum (https://electrum.org/#home) together with your nano s
to create such a transaction.
Your money is never lost.
You are still in control of your btc's until the transaction gets confirmed.
You can either wait until the transaction gets dropped out of the nodes mempool or perform a child-pays-for-parent.
A double-spending would be another options. But this would require to get this TX relayed to a miner who accepts 'conflicting' transactions.