PermissionError: [WinError 5] Access is denied: 'C:\\Windows\\SysWOW64\\electrum_data'
Of course, it wont be able to write the datadir in that protected Windows installation directory.
You can either:
- Move the portable electrum exe to a "normal" folder like "C://Program Files" (requires Administrator access) or to other partitions like "D:/".
There, Electrum-portable will be able to create its "electrum_data" datadir where settings, wallets and other data will be saved. - Or download and use the "Installer" (install it) or the "Stand-alone executable" so that the electrum datadir will be saved to its standard directory which is in "%appdata%" (roaming appdata)
Not mandatory for new Electrum download, but recommended: bitcoinelectrum.com/how-to-verify-your-electrum-download/