https://en.bitcoin.it/wiki/Running_Bitcoin
As for any other altcoins, you'd have to check on each of them individually. Some may implement similar options. Some may not. That's a question you'll have to ask in the alt-coin forum specifically for each one you are interested in.
Ahh okay thanks.
for BTC and LTC, I use electrum as I don't want to bog myself down with the block chain. Guess I'll have to look in individually for each altcoin.
to the sadness of our haters a new multi sig wallet called FrozenBit will be supporting Bitcoin Quark Litecoin and some others.
https://bitcointalksearch.org/topic/ann-frozenbit-multi-currency-multisignature-client-side-wallet-freenode-751248