-For Legacy : /m/44'/0'/0'
[...]
Safest way is to buy new hardware device(Ledger or Trezor) and just enter your seed,assuming that your lost Ledger have good pin protection and not to come to the hands of an experienced hacker(for which the possibility is very small).
If he uses the latest Electrum, it should show buttons which will allow him to choose correct derivation path. However, the last digit must be changed to access different accounts.
![](https://ip.bitcointalk.org/?u=https%3A%2F%2Fi.imgur.com%2FxdcwjxM.png&t=661&c=jjCzwu_jvYu8bA)
Ledger Nano S wipes itself if the PIN was entered incorrect 3 times. If he needs to access his funds anytime soon, he should do it on an offline computer and sign transactions only there.
Next time, consider using a passphrase for additional security! Ledger Nano S allows you to attach your passphrase to another PIN so you don't have to enter the whole word every time you reconnect your device.