There was a Twitter bot called "REKT" which trolled people who lost a ton of money at BITMEX. The bot itself is suspended afaik, but you can read some of the messages the bot posted here. The bot should be seen as a huge warning sign that a massive loss can happen as soon as someone starts to margin trade:
If you still want to try it anyway, I would advise you to start with very (!) small amounts, at a maximum 1% of your total trading capital. This way you can get over losses and still gain the necessary experience. I would only increase this amount after months of successful trading, never immediately after 1-2 lucky trades. Just my opinion as someone who had to learn those lessons already