ASUS Zenith Extreme TR4
-snip-
[Windows 10]
*Newest drivers
4 cards seems to work (10 min test)
5 cards unstable (crash after few mins)
Maybe this note from the motherboard's specification can explain it:
Since it only has 4 PCI-e x16 slots, I assume that you've connected a riser to the PCI-e x8 slot.
Mining will surely use it in x8 mode and will disable the U.2 port which is used by your SSD (you haven't specified if you're using SSD though, do you?).
Non-working 4 Cards with Linux however is weird, that board was designed to work with 4 cards.