If it uses an algorithm supported by ccminer then you should be able to mine it with nvOC. It most likely has a specific fork which performs better. If you find me the link to the clients repo and tell me what pool you want to / do use to mine skein, then I can add the client and modify oneBash for the next version.
In windows I use the alexis78 version from nemo's miner and I mine at Z-pool : https://bitcointalksearch.org/topic/nemosminer-multi-algo-profit-switching-nvidiacpu-miner-1777336
My batfile looks like this :
ccminerAlexis78.exe -r 0 -a skein -o stratum+tcp://skein.mine.zpool.ca:4933 -u BTC ADDDRESS -p c=BTC
https://github.com/alexis78/ccminer
Skein is paying really well atm...$23/1080ti/day
So I added this client and then tried to mine DGB with it; there is a problem: the linux version of this fork doesn't support skein.
wow that sucks, I'm doing about 2GH to 2.1GH on my 3x1080 TI rig on nvOC with intensity set to 26
Not sure how different that is from what the TP fork does; that's about 700 per 1080ti?