There are quite controversial experiences with Poloniex, some good, some bad. The fact that their fees are based on a relatively low percentage (15%) of the profit makes Poloniex a more approachable alternative. Nevertheless, what is your alternative to Poloniex then? (As you might notice, I need a decent almost real-time ticker with a programmer friendly API.)
let me tell you something about poloniex,
back then it's the best exchanger in my opinion,everything is very good and i am totally satisfied with their services,
but,something strange happened when they closed troll boxes,
when they did that,i encountered many people complained about their account or deposit/withdrawal process.
from the start i don't want to believe it,he/she might be a troller hired by someone or whatever.
but,in the next day i found another one that have an issue but he/she has a different issue from the first one.
and after that many people keep complaining about their account,
so i recommend you to not doing trade in there,i am afraid that they will 'take' your money with reason aka problem.
they can change their rules and terms as their wish,so something like that was not a big deal for them