Enabling pruning mode seems to prune the genesis block information, too. This block information needs to be available for P2Pool to verify the correct function of the rpc interface.
So in order to get P2Pool working with pruning mode enabled you have to keep the Bitcoin genesis block available for verification OR you have to modify your p2pool/bitcoin/networks/bitcoin.py file ...
This is incorrect. The genesis block is never inserted into the database. It's coinbase is never inserted into the database. The genesis block is hard coded into the client, it is not and cannot be pruned. So in order to get P2Pool working with pruning mode enabled you have to keep the Bitcoin genesis block available for verification OR you have to modify your p2pool/bitcoin/networks/bitcoin.py file ...
