Pretty much. You'd be surprised who won't send where. There are many, many sellers on Amazon US who won't send to the UK. Same goes for Newegg third party sellers. Bestbuy won't send to anywhere other than the US, Canada and Mexico and loads of other sites are the same.
And if you live somewhere like Morocco or something then it's goodnight completely for lots of stuff.
Another reason could be the buyer don't want provide his real address/name directly to seller (for w/e reasons) so using shipito as middlemen.
I'm with them for couple years, made like 5 shipments (from US to EU) and also never had any issue.
Couple years ago I actually purchased thing from US e-shop which had discounts for US deliveries and this almost covered shipping costs towards my place. So it was pretty good deal from my POV.
As an interesting note for very small items it's possible even omit the customs fee. (i've heard that somewhere so can't confirm it actually works).
When shipping small items like magazine, comic book, small parfume etc. Such things can be taken by person (courier) on board into carry-on package and can avoid duty as his personal item (then it's delivered to you by local post office).
But that way is occasional and can't guarantee you the delivery time (as they need to find the courier traveling to your destination).