Indeed, some states have stopped enforcing it, but the Feds still have a big hard-on for online gambling. And since it is pretty damn hard to do online gaming without crossing interstate lines, you are pretty much at the Feds mercy on this issue. Unless you are only dealing with gaming through a licensed business in your own state, that only uses online resources in your own state, and none of your data leaves the border of that state... you MIGHT be okay, if all taxes are paid, earnings reported on all sides, and nobody has ever jaywalked.
Otherwise, you would be well advised to add disclaimers that you are not offering the service to Americans in America. I'm just sayin'...
Ok i got your point.