What is Qubes OS? Is this another Linux OS like Debian, Ubuntu and Fedora? Or it has nothing to do with Linux OS (Standalone OS) out of the box? I actually like giving chance to new OS thats not windows OS, also what type of security you referring to? Is there any way I can read more about this Qubes OS?.
You can run Linux inside Qubes OS. So, the way it works is basically Qubes OS attempt to provide isolation via virtual machines, so you could have your USB virtual machine known as sys-usb, network, firewall, and then your operating systems all separated. It allows running of Fedora34 (or whatever the version is now), and Debian right out of the box, so the installer allows you to choose.
It requires a decent machine to run, and not all hardware is compatible. You'll need a CPU that supports virtualisation to start with. Although, while I consider Qubes OS the most secure way of going about things, it definitely isn't for everyone. I couldn't possibly touch upon everything, so refer to the links I've got below.
Although, if you're looking to effectively become your own bank, then I don't think security should be compromised. Technically, you could create a Bitcoin wallet on a offline "Qube" (which are the virtual machines), and never have that connect to the internet. So, effectively its a offline wallet, however you can copy the Bitcoin address easy using another Qube, and using the global copying system. So, there would be benefits of doing it on Qubes, but ultimately physical isolation is always more beneficial than system isolation like Qubes. Though, Qubes is better than just running a virtual machine via vmware or VirtualBox.
Qubes OS is my main operating system, although I don't use it for storing Bitcoin. I use physical isolation, which ultimately I would recommend over Qubes. Qubes though if you care about security, should probably be considered.
Luckily, despite Qubes OS being quite different from a normal OS, its got brilliant documentation. You can read about the general idea for security here:
https://www.qubes-os.org/doc/security-design-goals/ or if you want to dive deeper, check out the docs:
https://www.qubes-os.org/doc/