Regarding tokens and random shitcoins, I still don't see many options that are working well and open-source. I guess sticking to Trezor or similar is the only way to go right now?
Personally, I would say sticking to bitcoin is the way to go.
But yeah, if you want to buy random shitcoins, then chances are any wallets supporting said shitcoins are going to be similarly shit. Multi-coin hardware wallets are your best bet, but I wouldn't recommend either Ledger or Trezor given recent events from both companies. I have no idea which other hardware wallets are reputable and also support shitcoins.
I guess it's still very hard to find out in what way exactly it is skewed and then create an algo based on that info to take advantage to narrow down the actual seed-scope.
Well, it depends. In the case OP is discussing here, that is exactly what happened and multiple users had their funds stolen. If the RNG is weak but not weak enough to be compromised, we likely never hear of it.