The American healthcare system is rotten to the core. A limited subgroup of corporations are allowed to sell pharmaceutical drugs, and they take advantage of this policy and inflate the price by 10x or even 100x. Then there is insurance. The hospitals also inflate their bills by 5x or 10x, and the ordinary taxpayer ends up paying for all that. Still surprised that the US is having the highest medical insurance premiums in the world?
in all world only a limited subgroup of corporations are allowed to sell pharmaceutical drugs.
they make research = it's not free.
they make trial = you have also a good risk.
government doesn't pay for the physical development of new drugs, they pay after when drug could reach the market.
if you think that a drug could earn for 10-max 20 years, you can understand why there are this increase for pay drugs.