Keep your wallets on an encrypted disk (or in an encrypted container)... and block data elsewhere... that way your wallet files should be safe if the computer is physically compromised, but the encryption should not negatively effect performance when reading/writing to blockchain data.
I'm sure there will then be other gotcha's... like the ominous warning:
But as long as the FDE doesn't kick in during wallet operation... that shouldn't be an issue.
Because you are supposed to hide the fact that you own any bitcoins at all, and if the thieves see that you have the bitcoin blockchain, they will assume that you have bitcoins, even if you don't, which is possible that for some reason you have the blockchain but no bitcoins, but these goons will not care and will torture your ass until you give them your coins, and if you don't have any coins, you are fucked as well with no escape.
But I will not encrypt it, because I did some tests and it's way slower than normal, at least with my HDD and older computer, I guess it would be ok with modern computers, but I cant do it.
Now I just need to wipe the disks that I encrypted with Veracrypt and lost the passwords, but I dont really need them so I will leave them like that for now, there's nothing of value inside anyway.