First i need a bit of info:
What are the exact make/models of both cards?
What is your intensity, -g and thread concurrency set to?
Are you doing setx GPU_MAX_ALLOC_PERCENT 100 in a cmd window before running cgminer, then closing it, then opening a new cmd for cgminer?
What are your clock and voltage settings?
I am doing xset. My cards are both Gigabyte, one is a GHz edition, other one is regular. The GHz edition gets 660 at 1000core and 1500mem and the reguler one gets 600 at 900core and 1540 mem I have the intensities at 20. The thread concurrency is set to 20992 for both of them.