It can be happened to the new arrival casino's that they loose at their business because of the poor strategy and the management but if you see the large scale we can disagree with that there are most the casino's don't have loss yes they giving the jackpot and as well as the others prize but it after having their profits.
The house will always win is definitely real and as a gambler, we must already accept in ourselves that winning against it will be a risky task. We may need to spend a lot of money before that happens or worse, it won't happen at all in our whole gambling experience until we are wrecked.
The problem that I see is when the gambling site gives a gambler an initial win which could urge the gambler to play more and it will continuously happen until he tastes that win again. Greed will always come and avoiding that is difficult.