Ok this is not a black & white issue, there are nuances too.
For example we could classify the events in the following:
1) Supermassive Black Hole: Address without private key, an address which fits the format of bitcoin addresses, but whose private key cannot sign a transaction = Whatever coin is sent here, can't be sent out, unless ECDSA get's broken . IMPOSSIBLE TO RECOVER.
Ex:
https://blockchain.info/address/1BitcoinEaterAddress DontSendf59kuE
2) Regular Black Hole: Address with private key, but which's private key is lost beyond recovery, and no plausible backup exists:
Ex: -Throwaway addresses of blockchain.info with small satoshis left on them that you delete
-1 Wallet file with password wrote down on piece of paper, but no other backup. Hard disk burns down, coins lost forever.
HIGHLY UNLIKELY TO RECOVER, UNLESS YOU CAN RECOVER DATA FROM BROKEN HARD DISK
3) Supernova Address: Address with private key, where the key is temporarly or for a longer time inaccesible, but it can be recovered later
Ex: Electrum seed wrote down on a piece of paper , no digital wallet file, the paper is lost, but still in your house. After 3-4 years you find the piece of paper and access your coins again.
EASY TO RECOVER BUT ONLY AFTER A TIME
4) Dormant Address: Address with known private key, fully accessible for the owner, but he doesnt touch it for a longer time
Ex: Long term savings account in bitcoin, Hodlers, etc...
5) Hot Address: Addresses that send and receive transactions and bitcoins are frequently moved from here
Now here are the implications:
1) and 2) are plausibly unbreakable. And from economic POV, it does help add to scarcity and make price go up in the longterm
3) and 4) is also good but it only serves a temporary role in this, however if different people do it in different times, then the net result is still positive and it adds to scarcity.
It's better if a person buys 1 BTC and sells it 1 minute later, than if he didnt bought it in th first place. Even just holding it for 1 minute benefits the community, so those 3-4 year long term holders are evidently good, and add to scarcity.
5) This is not good, but bitcoin still needs active users, to maintain active demand, but in this research we will only focus on the supply side.