Depends on what you are offering or selling. If you are selling items that are in demand then the possible huge profit can be seen. Aside from that take note of the volatility of Bitcoin. If you have a huge capital you can stock up Bitcoin and use your fiat currency to resupply your business. Then the moment Bitcoin price increase, you can then sell those BTC for extra income. It is up to your strategy on how you will greatly profit on venturing a business with Bitcoin as mode of payment.
but if we do some business or take a sallary in bitcoin when the price in 18k usd and then now the price is around 13k usd... it will bad for business
too much price gap is bad for constant business except investing business