"Suddenly" is not going to work here for a number of reasons, the main one being the chances of matching up someone prepared to source and sink such large sums in Bitcoin and who happens to want to exchange a house are small, "Gradually" could work though, in a number of different ways.
1) Gradual purchase or combined rent/buy. I have never done this but I think it has a huge capability to offere advantages to both buyer and seller even without bitcoins.
It does need to be drafted fairly, and so seller and buyer need to have enough sense to recognise when this is not the case.
In this scheme the purchaser effectively gives the purchaser a mortgage on the house and agrees to rent it to them for a period of time, say 15 years. There is also a deed of sale to sell the house in 15 years time for a nominal sum, provided that rent has never fallen significantly in arrears. The rental agreement allows the seller to evict the purchaser if "rent" is not paid, under certain conditions.
Advantages of the scheme: The buyer does not need to come up suddenly with large amounts of Bitcoin which is tricky if you have not already got them. There is no 3rd party mortgage company involved. Steady bitcoin income for the seller (probably denominated in fiat.)
2) Part of the price is paid in bitcoin. Advantageous to the seller because the registered sale price is reduced, so capital gains and capital transfer tax is reduced. (Assuming tax is NOT paid on the Bitcoin part of the transaction. ) Advantage to buyer: capital transfer tax reduced, capital gains tax liability is transferred.
1) & 2) can be combined of course.
Or via an entirely different process altogether, with the net result being an individual owns outright a home paid entirely with bitcoins to a Real Estate agent in one of the 50 US states, where said agent has a Bitcoin payment option on their respective website.
I did not mean to suggest that my suggestion was the only one, of course there are other possibilities. Its just one of the problems is that even for a modest house, its quite a lot of bitcoins!!
As a child, I always used to dream of walking into one of these smug looking estate agents offices, you know the one where they try to look too important and busy to even serve you. It would be even more fun to do this as as a child of course. I'd walk in with a suitcase, and without viewing or anything say, Yeah, I want that one there, and then proceed to pay the asking price in cash to the man at the desk. I need to move in tonight though, I'd say. I dont know if they would do it I suppose in fact they would bite your arm off because cash buyers are so very few and far between.
Knowing what I know now about real estate, I can say that simple deals are few and far between, and cash buyers rare. Many deals barely creak through, and I live in London (Uk) where the market is pretty buoyant. Adding Bitcoin into the mix as I see it can only make it harder.
I think it would be a great thing to set up, but I think if you are realistic about it it would be tricky to do. Not a reason not to try of course.