Danny Garcia has never fought at middleweight and that is why Lara is the favorite. Both are well past their prime and are older in age so I would expect this to be a slow paced fight. They have both been semi-retired but whoever looses should definitely retire for good. I imagine the winner will have the opportunity to unify with Adames, although I have doubts if Danny Garcia still has the motivation to continue. Even if he wins, he might choose to retire and go out as a champion.
Both might be past their prime, but Lara is more active than Garcia hence, that might be a big factor on this upcoming classical match.
I still remember how slick Lara is and how good he is on defense, but it's been a long time since he got a big fight, and so does Garcia that hasn't been on the ring for around 2 years. That might affect his performance coming to this fight, and the fact that he never had a fight on Middleweight division is also a factor as well.
Nevertheless, this is a make or break decision for Garcia. 3 fights in the last 4 years (this would be the 4th one) for me isn't a good sign. I mean it would be better if you're still active, fighting at least once or twice per year. If Lara has a disadvantage for this match, that would be the age, but his active still so I don't see it that much of a problem from him.
If I will predict between the two, I'd go with Lara as well, but let's enjoy the fight still.