You should always try your best to get the bonus (reference: https://www.bustabit.com/faq#last) so to overcome the house edge of the game. What you should do to achieve that depends on the the other players' bet sizes and cashout points.
But I think the bonus is not too high compare to what you lose. The more multiplier you get the higher the bonus right? So try to keep aim bonus is not really useful. Usually I played low after sometimes then try to hit higher multiplier. It works better most of the time
To your question of "The more multiplier you get the higher the bonus right?", the answer is "not necessarily". For example, if you are having the biggest bet size in that round, you will get the max bonus as long as you are the last one to cash out. On the other hand, if you are not the biggest bettor in the round, you could cashout "midway". Also, the house edge of bustabit is from 0% to 1% depending on your cashout point, and the bonus could be a lot higher than the house edge, making the game +EV.
You have to be the last big bettor ( not necessarily the last bettor) to catch the biggest chunk of the bonus ... if I got it right