What effects, both positive and negative, does the fact that a substantial proportion of people that invest or get involved with Bitcoin in the first place, have the intention of making profit in a fiat currency as their primary objective? There are many people who do not fall within this category and many, who start in this manner, that then take on other ideals and ambitions. There are also many who want to "cash in, cash out".
The fact that it's very easy to buy and sell Bitcoin for fiat is positive because it gives people reassurance that it's something valuable and that they will be able to fall back on fiat if they feel like it. The fact that people tend to care about profit in fiat and don't see Bitcoin as valuable on its own is sad because it means many don't care what Bitcoin offers but instead see it merely as a means to get rich and to use the real money (which for them is fiat) to buy things.
So it's encouraging to see companies accept Bitcoin as money, but given how limited these options are, some people might be so fiat-focused because they don't see it changing, not because they wouldn't want it to change and wouldn't be willing to use Bitcoin directly under different circumstances.