There is alot of sites which trade CSGO skins into crypto. We can then bet the crypto on CSGO games, so its just more indirect.
Online would be higher latency, the main problem is entirely different regions. If the ping is over 50 it starts to be a factor that can unbalance the game. CSGO with global in the name does do alot to account for variation geographically but yes its a factor for sure. It can alter tactics, play style and team superiority I think, its not entirely clear because it depends on training and planning to include this factor. Peekers advantage is a massive deal in CSGO and considered OP by most (over powered).