Binance has already established itself as the biggest centralized exchange in terms of volume and users on a global scale. The stepping down of CZ will affect a bit its operation and business, of course, but in the long run as long as the CEO is good then it will even be growing more. I have a lot of confidence on Binance and remember that the hack that happened to it in the past never made long-term negative effect on its growth...and I am hoping the same.
I believe CZ is only officially resigned but inside the house he's still the CEO and Richard is only representing CZ. From what I checked Richard Tang do have the expertise and qualifications to handle the affairs of Binance but CZ's experience still remains the irreplaceable commodity needed to pilot the affairs of Binance, I believe CZ will still remain the brain behind the whole operation while Richard Tang will only be standing for him as the CEO. So I have no doubt that Binance's operation would still be as usual and we wouldn't need to worry about the change in government.