2016 doesn't seem so random to me. There are exactly 20160 minutes in 2 weeks.
Very good point!
This exactly says the 2016 is related to the 10 minutes block time an and the difficulty re-target of 2 weeks.
A serious answer why this number is 2016 seems not possible without noticing this other both values
I took a numerology course last year and it is clear there is a message here:
2016 = 2 ** 11 - (2 ** 5)
Remove the noisy signs and we get
2016 11 05
There are two important events that day:
* The Silk Road Conference (http://www.uncon-conv.com/silkroad-main-2016/) and,
* The Kobe Convention Center, the Asian Pacific Digestive Week (http://www.apdw2016.org/congress.html).
Just coincidence?