so based on the comments so far, 4gb flash drive is minimum for mining? i think i remember seeing people use a very small footprint of 512mb or 1gb space on linux for crunching or folding setups for both the CPU and GPU
just a little reality check, you're not going to gain that much.
even if you were running a ridiculous hard drive like a seagate cheetah 15k, you'll only gain about 5 or so watts by switching to a flash drive.
If your rig is anything like mine (single 6870, about 300W total system draw while mining), that's about 1.6% hashes/joule efficiency gained, and less if you're running multiple cards.
it's not about the extra power draw difference between a mechanical HD and a flash drive, it's about cost and setup. it'd rather spend $5-10 on a flash drive than a cheap $30 hard drive, and also when the mining hardware just lays on the table, it saves a little bit of space, especially when having multiple mining setups on the same table.