No, I don't think that it could help, knowledge in what you are playing would only possibly have a good effect if it is sports gambling, but still, as they say, the ball is round, so there is still a chance to fail...Besides, on dice games knowledge won't help..
True. In gambling knowledge will not help much instead only luck can bring more profits for any one. If we know this fact then we shouldn't gamble every day to make profits instead gamble some times to check your luck. I don't think, is there any think called safe in gambling so if you really want to be safe then don't ever gamble.