Gambling will never be safe because this thing is all about risking money. If you want to profit with a safe thing then don't gamble better go for investment because gambling is always all about losing and risking your bankroll but if you just want safe methods then control your emotions and have a discipline when it comes to gambling.
Gambling maybe labeled as high risk but there are ways to minimize it. This may not guarantee a win but at least the method can minimize your lost.
1. Use money that you don't need. Money that is allocated to bills and family needs must not be used.
2. Dont bet blindlessly or don't rely too much on tips if you are into sports betting.
3. Always think that every roll have different result.
4. Do not randomly change your stakes, you must have staking system
5. Don't be affected by emotions, you should be calm when you are betting.
6. Never bet on a game you do not understand.
This are some of the possible way to minimize your loses.