Anything can happen in those 2 games but if the 2 big teams will lose they will in a bad spot for the rest of the Season.
This will be the real test for Pirlo, Juventus lost 3 times the last year with Lazio if I can remebember correctly.
For the juventus , it should be a tight win over lazio but i wont too overconfident , they often makes a surprise. Hard choice but for me it is clear a win for juventus.