I prefer sites that use large Cryptocurrencies platform, you will always have an option to use other tokens/coins when you run out of the other tokens/coins, there are advantages and disadvantages of playing in Gambling sites that use their own token, especially for a new gambling site that uses their own token, they can only be traded in a few low levels exchange some people don't want to go to a low level exchanges to deposit funds and trade there.
Another disadvantage is fluctuation of the price of the token you don't want to play in one token/coin if the price is fluctuating, you rather play using a token with a good price in the market.