Arsenal and MU have changed so much this season. The Gunners are even now incarnated as strong candidates for the Premier League title and Arsenal will clearly dominate the game more because they are playing at home. However, MU, which is now much more solid, will provide commensurate resistance.
Casemiro's absence is also an obstacle for MU. It will be easier for Arsenal to control the midfield in the match duel later, but MU can spread danger through counterattack schemes that Arsenal must be aware of. I predict this game will end in a draw or Arsenal will win narrowly.
With Manchester United will focusing on defensive play, Casemiro's absence could be very tangible for them. But even more important in this game will be how Manchester United will be able to implement counterattacks today. Rashford has good speed and ten Hag can count on him today, there may not be many chances, so they need to try to convert them. Manchester United was difficult to play with Crystal Palace, and most likely it will be even more difficult with Arsenal.
Their first encounter this season saw Antony come in as substitute to find the back of the net. Am not hoping the score line is against Arsenal, but with statistics, Manchester United have been the better side during such an encounter. I don't seem to know how they have Arsenals Achilles heel under check, but am hoping Arsenal does me proud by whopping Manchester United with an above >2.5goal margin.
In the absence of Gabriel so far, Casemiro and Martial, I think the performance of both teams goes beyond individual players, rather, it is more team effort and great insight of the Managers.