Manchester Utd need to win this desperately not to be left behind more by City. If City lose points in the match against West Ham, it will also be a chance for Man Utd to reduce the point difference. However, Chelsea have been really great in the recent times. They haven't lost for 6 matches in the EPL and they defeated Atletico in the CL match 1-0 last. I am expecting both teams to score and a tie at the end.
A draw between United and Chelsea will fall in favor of Manchester City, City are up against a very strong West Ham side this season, but I have no doubts that they'll be put aside by Pep's side, City are absolutely so strong for the rest of the teams in the league, I think City's next loss could even come when the league is already wrapped up and it's no longer possible for anyone to finish above them, it's going to be a top four race for the rest of the top teams soon.
Having said that, Liverpool face Sheffield United, and after a good performance in the CL in mid-week, they'll have to win this game against relegated threatened Sheffield if they are to have any chance of finishing in any of the top four positions.