This statement about "most efficient" is not actually true, but it's interesting to hear from people who are shutting down and throwing in the towel, and why, and so on.
FWIW, it is still possible for long-term mining individuals to rule the roost, so to speak, in comparison to people with rent/property tax/staffing costs. I would say the people who are using the profits from prior mining efforts have a significant advantage to the newbs who are going into the red to buy up ASIC.
For people who are still in the black after the pre-order frenzies? Everything the ASICs make is technically a net profit from The Mining Operation, counting from day-0. "Still ahead, gonna stay there until it can't pay for its own expansion."
My advice for newbs trying to do it semi-seriously, or for midsized profits by climbing into the pre-order lists this late? For competing?
Too late. You now have two significant disadvantages and you haven't even turned on a miner yet.
Here's the only reason these people should be trying to get ahold of ASIC: They want pristine coins with no history, and in small amounts they can use to buy small things, or want to get ahold of a handful of Bitcoins for long-term long-haul storage. It is a deflationary currency after all.