I do not understand why people are looking into hyped stuff like defi, they are here for right now but they will not be as big of a deal as they are for a long period of time. In any case if you want to use masternodes or proof of stake and take out the profit and continue with the rest, it may work for a while but do not forget that other people are using those profits to grow their lead bigger and you will make less and less because you are not reinvesting.
So, I would suggest unless you need the money for something, don't do that and reinvest all the money back into the stake or masternode you are doing. Otherwise you are not going to have a lot of money and if the coin itself drops in value as well you are going to basically be losing money let alone making any profit.
95% of all Defi, masternodes and staking project are hype base and with the altcoin market been highly manipulated making long term investment could lead to losses. So, I dont the reinvest all money back as something and cashing out when the target reach while invest in BTC is a better decision.
@OP, Instead of base only in staking, masternode and lending while dont you trade crypto, there are some crypto exchange site that offer free trading bot service.