In this stadium, we can say that people who took loans to invest in crypto are in profit! More specifically people who did that before 2020! It's a risky investment, I agree with that part, but if you believe in something if you plan to invest in the long run then it's a different story! Now it's a bearish period, and the price can drop more, who knows, to take advantage of "buy the deep" you will have to have money at the specific moment, if you don't have it I guess it's ok to take one that you will repay from your salary in a year or two, and you will have your investment for the future!
The same could be said in reverse for people who did it in 2021 though. Like if they got a loan and bought at 60k then they are in a big big loss right now, not only they will fail to pay their loan back, but they will also fail to make any profit at all as well. Remember, these people who take a loan, pays with interest back as well, so if it is a long term deal, then they would eventually have to spend that money on regular life stuff that they can't right now.
Just to give an example, I need only 200 bucks to pay off my debt leftover, I paid everything else, and I am doing pretty well for myself, and the only payment I make right now is like 70 bucks a month, for another 3 months and I am done with it, and yet I am still not paying it full even if I can. Because, I want my cash with me to survive, that extra 140 bucks is needed to survive, and you are telling me people would pay it back in full if they profit or loss? Doubt so.