By definition no, but in practice sort of.
I have been largely painting this fungibility topic with broad strokes regarding what seems to be a topic that attempts to spread FUD rather than treating an actual serious bitcoin issue which fungibility currently is not such a topic, even though surely there are likely going to be attempted bitcoin fungibility attacks in the future - whether informationally or the employment of various methods, like you suggested blacklisting as one possible method that may not be easy to carry out in bitcoin if "people-empowering" tools continue to be developed and evolve.
Unfortunately my faith in that area is that it will be tested and I hope those tools you speak of materialize. Right now it's kind of ironic that non fungible coins are similar to fiat by being sort of. But I don't see how not being fungible can destroy any coin it just has a different utility.